Lymphodepletion-for-CAR-T-Outcomes

ABOUT THE WEBINAR

Achieving consistent and effective outcomes in CAR T and other immune effector cell (IEC) therapies relies heavily on getting lymphodepletion “right.” Emerging evidence shows that both under- and over-exposure can impact safety, efficacy, and long-term persistence, making optimized dosing strategies increasingly critical as the field evolves.

This webinar will explore how model-informed and data-driven approaches can help identify the optimal lymphodepletion exposure window, improve predictability, and support more standardized practices across patient populations and treatment centers. Speakers will discuss current challenges, scientific rationale, clinical insights, and practical considerations for implementation.

Log in to your ISCT Member Account to access the webinar.

 WEBINAR CHAIRS

Jaap Jan Boelens, MD, PhD
ISCT North America Regional Vice President
Chief of the Pediatric Transplantation and Cellular Therapies Service
Memorial Sloan Kettering Cancer Center (MSKCC)
United States

Kevin Curran, MD
Pediatric Hematologist-Oncologist
Memorial Sloan Kettering Cancer Center (MSKCC)
United States

 WEBINAR SPEAKERS

Frisco Calkoen, MD, PhD
 Pediatric Oncologist
Princess Maxima Center
Netherlands

Rick Admiraal, MD, PhD
 Clinical Research Fellow, Pediatric Oncology
Princess Maxima Center
Netherlands

Benno Lickefett, MD
 Resident, Hematology-Oncology
University Hospital of Hamburg
Germany