Program

The Sweden Ecosystem: A Route from Concept Creation to Product Delivery

CHAIR: Johan Hyllner, PhD, AstraZeneca/Linköping University, Gothenburg, Sweden

SPEAKERS: 

• Kristina Levan, PhD, ATMP Sweden, Sahlgrenska University Hospital, Sweden
• Anna Falk, PhD, Lund University/CCRM Nordic, Sweden
• Veronique Chotteau, PhD, KTH Royal Institute of Technology/AdBIOPRO, Sweden

Current Use of iPSC to Fill Unmet Clinical Gaps

CHAIR: Anna Falk, PhD, Lund University/CCRM Nordic, Sweden  

SPEAKERS:

• Jacqueline Barry, PhD, Cell and Gene Therapy Catapult, United Kingdom 
• Begoña Aran, PhD, Bellvitge Biomedical Research Institute (IDIBELL), Spain
• Massimiliano Gnecchi, MD, PhD, University of Pavia, Italy

Understanding and Developing Your Manufacturing Process - From Phase I to Commercialisation

CHAIR: Ricardo Baptista, PhD, SmartCella, Sweden

SPEAKERS: 

• Marcia Mata, PhD, Cell and Gene Therapy Catapult, United Kingdom
• Sven Verguts, PhD, Merck Group, Belgium 
• Rob Allen, PhD, DHC Europe Ltd - Dark Horse Consulting, United Kingdom

Innovations in TIL Therapy: Melanoma Trials and Beyond

CO-CHAIRS: 

• Erja Kerkela, PhD, Finnish Red Cross Blood Service, Finland
  
• Anna Pasetto, PhD, Oslo University Hospital, Norway

SPEAKERS: 

• Özcan Met, PhD, Herlev and Gentofte Hospital, Center for Cancer Immune Therapy (CCIT-DK), Denmark
• Stina Wickström, PhD, Department of Oncology-Pathology, Karolinska Institute, Sweden
• Victor Cervera, PhD, Tilt Biotherapeutics, Finland

Breaking Manufacturing Boundaries: Who Will Conquer the Scalability Strategy?

CHAIR: Michael Delahaye, EngD, AstraZeneca, Sweden

SPEAKER: 

• Hollie Bartley, BSc, Resolution Therapeutics, United Kingdom 
• Robert Zweigerdt, PhD, Hannover Medical School (MHH), Germany 
• Daria Donati, PhD, Cytiva, Sweden

Application of Mesenchymal Stromal Cells - Focusing on the Clinical Indication

CHAIR: Lindsay Davies, PhD, FHEA, NextCell Pharma, Sweden

SPEAKERS: 

• Dominique Farge, MD, PhD, Université Paris-Cité, AP-HP, France
• Lindsay Davies, PhD, FHEA, NextCell Pharma, Sweden
• Damian García Olmo, MD, PhD, Autonomous University of Madrid, Spain

Regulatory Considerations for Early Development in the CGT Product Lifecycle

CHAIR: Margareth Jorvid, MSc Pharm, MSc MTRA, MBA, Methra Uppsala AB, Sweden

SPEAKERS: 

• Patrick Celis, PhD, European Medicines Agency (EMA), Netherlands
• Miguel Forte, MD, PhD, mC4Tx, Belgium
• Anna Koptina Gültekin, PhD, Mendus AB, Sweden

ISCT-ISEV Joint Session: Advancing the Translation of Extracellular Vesicle and Secretome-Based Therapeutics

CO-CHAIRS: 

• Massimiliano Gnecchi, MD, PhD, ISCT Chief Scientific Officer, University of Pavia, Italy
  
• Benedetta Bussolati, MD, PhD, President-Elect of the International Society for Extracellular Vesicles, University of Turin, Italy

SPEAKER: 

• Benedetta Bussolati, MD, PhD, President-Elect of the International Society for Extracellular Vesicles, University of Turin, Italy
• Jan Lötvall, MD, PhD, University of Gothenburg, Sweden 
• Bernd Giebel, PhD, University of Duisburg-Essen, Germany 

Standardisation: A Cornerstone of Product Efficacy and Safety

CHAIR: Elsa Abranches, PhD, AstraZeneca, Sweden

SPEAKER: 

• Jonathan Campbell, PhD, MetBio Scientific Consulting, United Kingdom
• Peter Crowley, BSc(Hons), Medicines and Healthcare products Regulatory Agency (MHRA), United Kingdom 
• Ivana Knezevic, MD, PhD, World Health Organization (WHO), Switzerland

EU LRA Concurrent Session
Raw and Starting Material Challenges in CAR-T Manufacturing

CHAIR:

• Bernd Schröder, PhD, Miltenyi Biotec B.V. & Co. KG, Germany
• Carmen Sanges, PhD, Universitätsklinikum Würzburg, Germany 

SPEAKER: 

• Carole Moukheiber, PharmD, Servier, France
• Bernd Schröder, PhD, Miltenyi Biotec B.V. & Co. KG, Germany
• Nina Worel, MD, PhD, Medical University of Vienna, Austria

PANELIST: 

• Manel Juan, MD, PhD, Hospital Clinic Barcelona, Spain 

Genetic Engineering Approaches: A Biological Recipe to Gene-Modified Cell Therapies

CHAIR: Vincenzo Di Cerbo, PhD, Cell and Gene Therapy Catapult, United Kingdom

SPEAKERS: 

• Benjamin Klapholz, PhD, bit.bio, United Kingdom
• Luke Pase, PhD, Anocca AB, Sweden 
• Vlad Seitan, PhD, Laverock Therapeutics, United Kingdom 

ATMP Regulatory Interplay: Difficulties in Navigating Quality and Regulatory Standards of Cell-Based Starting Materials in an Era of Regulatory Resilience and Harmonization

CHAIR: Michela Gabaldo, PharmD, EVOTEC, Italy

SPEAKERS: 

• Ilona Reischl, PhD, Assessor, AGES, MEA, Austria
• Stefaan van der Spiegel, MD, MBA, European Commission, Belgium

PANELISTS: 

• Jacqueline Barry, PhD, Cell and Gene Therapy Catapult, United Kingdom 
• Nina Worel, MD, PhD, Medical University of Vienna, Austria

Cell and Gene Therapy Cold Chain Management: From Logistics to Product Design

CHAIR: Dominic Clarke, PhD, Cryoport Systems, United States

SPEAKERS: 

• Lindsay Davies, PhD, FHEA, NextCell Pharma, Sweden
• Ivo Urh, MSc, Fujifilm Irvine Scientific, London, United Kingdom
• Dominic Clarke, PhD, Cryoport Systems, United States

Stem Cell Based Gene Therapy, the Promise of a Life-Long Cure?

CHAIR: Jaap Jan Zwaginga, MD, PhD, Leiden University, Netherlands

SPEAKERS: 

• Marina Cavazzana, MD, PhD, Département de Biothérapie - Hôpital Necker-Enfants Malades, Assistance Publique–Hôpitaux de Paris, Centre d’Investigation Clinique en Biothérapie, INSERM VMR1163, Imagine Institute, Université Paris-Cité, France
• Johan Flygare, MD, PhD, Lund University, Sweden
• Frank J.T. Staal, PhD, Leiden University Medical Center, Netherlands

Improving AAV Vector Designs: New Concepts for Gene Therapy Translation

CHAIR: 

• Vincenzo Di Cerbo, PhD, Cell and Gene Therapy Catapult, United Kingdom 

SPEAKER: 

• Ana Sofia Coroadinha, PhD, iBET - Instituto de Biologia Experimental e Tecnológica, Portugal
• Andy Murray, PhD, Sania Tx, United Kingdom 
• Ambra Cappelletto, PhD, Purespring Therapeutics, United Kingdom