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Review

Rheumatoid arthritis: From synovium biology to cell-based therapy
Michaela Debreova, Martina Culenova, Veronika Smolinska, Andreas Nicodemou, Maria Csobonyeiova, Lubos Danisovic

Current protocols and clinical efficacy of human fetal liver cell therapy in patients with liver disease: A literature review
Antonella Giancotti, Valentina D'Ambrosio, Sara Corno, Cristina Pajno, Guido Carpino, Gaia Amato, Flaminia Vena, Alessandro Mondo, Lorenzo Spiniello, Marco Monti, Ludovico Muzii, Daniela Bosco, Eugenio Gaudio, Domenico Alvaro, Vincenzo Cardinale

ISCT Committee Paper

An ISCT Stem Cell Engineering Committee Position Statement on Immune Reconstitution: the importance of predictable and modifiable milestones of immune reconstitution to transplant outcomes
Alice Bertaina, Allistair Abraham, Carmem Bonfim, Sandra Cohen, Duncan Purtill, Annalisa Ruggeri, Daniel Weiss, Robert Wynn, Jaap Jan Boelens, Susan Prockop

Full-Length Articles

Basic Research

Identification of alpha-enolase as a potential immunogenic molecule during allogeneic transplantation of human adipose-derived mesenchymal stromal cells
Dongdong Wang, Yi Fu, Junfen Fan, Yue Wang, Chao Li, Yi Xu, Hui Chen, Yu Hu, Hongcui Cao, Robert Chunhua Zhao, Wei He, Jianmin Zhang

Translational Research

Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies
Harinad B. Maganti, Aidan M. Kirkham, Adrian J.M. Bailey, Risa Shorr, Natasha Kekre, Nicolas Pineault, David S. Allan

Impact of FLT3 internal tandem duplication and NPM1 mutations in acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation
Rutvij A. Khanolkar, Rehan M. Faridi, Megan Kinzel, Kareem Jamani, Mary L. Savoie, Mona Shafey, Faisal M. Khan, Jan Storek

Clinical Research

Prevention of chronic diabetic complications in type 1 diabetes by co-transplantation of umbilical cord mesenchymal stromal cells and autologous bone marrow: a pilot randomized controlled open-label clinical study with 8-year follow-up
Zhixian Wu, Xiumin Xu, Jinquan Cai, Jin Chen, Lianghu Huang, Weizhen Wu, Alberto Pugliese, Shasha Li, Camillo Ricordi, Jianming Tan

Time to initiation of pre-emptive therapy for cytomegalovirus impacts overall survival in pediatric hematopoietic stem cell transplant recipients
Christine Camacho-Bydume, Audrey Mauguen, M. Irene Rodriguez-Sanchez, Elizabeth Klein, Nancy A. Kernan, Susan Prockop, Jaap Jan Boelens, Genovefa A. Papanicolaou, Maria Cancio

Manufacturing

Meeting the COVID challenge: Optimizing vCD34⁺ in cryopreserved HPC samples for implementation of an external QA Program
Annabella Chang, Scott J. Ragg, David D. Ma