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In this "From the President's Desk" submission, Miguel Forte examines the promise of gene therapy alongside the ethical and regulatory challenges it presents. From advancements in somatic therapies to the complexities of germline editing, this piece addresses the evolving landscape of gene editing, emphasizing the importance of responsible governance to ensure these transformative therapies are developed safely and ethically. Read More

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In this article, Dr. Adaeze Ekwe explores the groundbreaking progress and challenges of cellular therapies in treating solid tumors. Highlighting recent FDA approvals of AMTAGVI and TECELRA, Dr. Ekwe details the impact of TIL and TCR-engineered therapies on cancers like advanced melanoma and sarcoma. With a look at the hurdles of manufacturing, cost, and accessibility, this article underscores the vital role of continued innovation to make these transformative therapies more broadly available and effective for patients. Read More

The Telegraft presents another live interview with a first-time ISCT Annual Meeting attendee who took home a top prize. Dr. Renault spoke with Telegraft Editor, Dr. Ashley Krull, Ph.D., in person at the annual meeting and shared more about her award-winning work examining a first-in-human treatment of heart failure using the secretome of iPSC-derived cardiovascular progenitor cells. Read More

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ISCT 2024 Annual Meeting