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June 2022 (Volume 24, Issue 6) Now Available

June 2022 (Volume 24, Issue 6)


CAR T targets and microenvironmental barriers of osteosarcoma
Jiawen Zhu, Nafeisha· Simayi, Rongxue Wan, Wenhua Huang

Standardization of cellular therapy terminology, coding and labeling: a review
Paul Ashford, Sallie Allman, Stella Larsson, Kathy Loper, Karen Moniz, Leigh Sims-Poston, Ineke Slaper-Cortenbach, Zbigniew M. Szczepiorkowski
Open Access

ISCT Committee Paper

Impact considerations of post-production processes on cell and gene drug products
John Fink, Michael Scott, Sebastian Rieck, Robert Jones, Jean-Sebastian Parisse, Heidi Hagen, Yonatan Lipsitz, Steve Oh, Dominic Clarke

Short Report

Design of experiments as a decision tool for cell therapy manufacturing
Esmond Lee, Devin Shah, Matthew Porteus, J. Fraser Wright, Rosa Bacchetta

Full-Length Articles

Basic Research

Dental pulp stem cell-derived extracellular matrix: autologous tool boosting bone regeneration
Milda Alksne, Migle Kalvaityte, Egidijus Simoliunas, Ieva Gendviliene, Povilas Barasa, Ieva Rinkunaite, Algirdas Kaupinis, Dmitrij Seinin, Vygandas Rutkunas, Virginija Bukelskiene

Characterizing human mesenchymal stromal cells’ immune-modulatory potency using targeted lipidomic profiling of sphingolipids
S'Dravious A. DeVeaux, Molly E. Ogle, Sofiya Vyshnya, Nathan F. Chiappa, Bobby Leitmann, Ryan Rudy, Abigail Day, Luke J. Mortensen, Joanne Kurtzberg, Krishnendu Roy, Edward A. Botchwey

Imaging flow cytometry challenges the usefulness of classically used extracellular vesicle labeling dyes and qualifies the novel dye Exoria for the labeling of mesenchymal stromal cell–extracellular vesicle preparations
Tobias Tertel, Melanie Schoppet, Oumaima Stambouli, Ali Al-Jipouri, Patrick F. James, Bernd Giebel
Open Access

Translational Research

Understanding potential barriers and enablers to a perioperative early phase cell therapy trial
Madison Foster, Dean A. Fergusson, Victoria Hunniford, Analyssa Cardenas, Gisell Castillo, Judith Yaworsky, C. David Mazer, P.J. Devereaux, Daniel I. McIsaac, Duncan J. Stewart, Justin Presseau, Manoj M. Lalu
Open Access

Clinical Research

Mesenchymal stem/stromal cell–based therapies for COVID-19: First iteration of a living systematic review and meta-analysis: MSCs and COVID-19
Aidan M. Kirkham, Madeline Monaghan, Adrian J.M. Bailey, Risa Shorr, Manoj M. Lalu, Dean A. Fergusson, David S. Allan

Improving cell viability using counterflow centrifugal elutriation
Anqi Li, Mehri Barabadi, Hannah McDonald, Siow Teng Chan, Mirja Krause, Joshua D. Ooi, Gina D. Kusuma, David James, Rebecca Lim
Open Access


Engineering of regulatory T cells by means of mRNA electroporation in a GMP-compliant manner
Ibo Janssens, Diana Campillo Davó, Jasper Van den Bos, Hans De Reu, Zwi N. Berneman, Inez Wens, Nathalie Cools
Open Access



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