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Letter to the Editor
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The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation
Michael Halpenny, Nishaka William, Heidi Elmoazzen, Antonio Giulivi, Lisa Martin, Donna Perron, Christopher Bredeson, Linda Hamelin, Lothar Huebsch, Lin Yang, Paul Birch, Jason P. Acker
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Reviews
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The safety and efficacy of mesenchymal stem cell therapy in diabetic lower extremity vascular disease: a meta-analysis and systematic review
Lewei Jin, Xiancheng Wang, Zhihua Qiao, Yiwen Deng
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Induced pluripotent stem cell-based disease modeling and prospective immune therapy for coronavirus disease 2019
Koushik Chakrabarty, Rohit Shetty, Shubham Argulwar, Debashish Das, Arkasubhra Ghosh
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Curative therapy for hemoglobinopathies: an International Society for Cell & Gene Therapy Stem Cell Engineering Committee review comparing outcomes, accessibility and cost of ex vivo stem cell gene therapy versus allogeneic hematopoietic stem cell transplantation
Alexis Leonard, Alice Bertaina, Carmem Bonfim, Sandra Cohen, Susan Prockop, Duncan Purtill, Athena Russell, Jaap Jan Boelens, Robert Wynn, Annalisa Ruggeri, Allistair Abraham
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Full-Length Articles
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Basic Research
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Endothelial nitric oxide synthase-engineered mesenchymal stromal cells induce anti-inflammation in experimental immune models
Jennifer A. Korchak, Mina Delawary, Peng Huang, Cuiping Zhang, Koji Suda, Abba Chedi Zubair
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Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts
Richa Kaushal, Suria Jahan, Chelsea McGregor, Nicolas Pineault
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Combinatorial antigen targeting strategies for acute leukemia: application in myeloid malignancy
Pinar Ataca Atilla, Mary K. McKenna, Norihiro Watanabe, Maksim Mamonkin, Malcolm K. Brenner, Erden Atilla
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Translational Research
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Coupling programmed cell death 1-positive tumor-infiltrating T cells with anti-programmed cell death 1 antibody improves the efficacy of adoptive T-cell therapy
Jiacheng Chu, Chenya Wang, Qingle Ma, Huaxing Dai, Jialu Xu, Edikan A. Ogunnaike, Fei Peng, Xiaolin Shi, Chao Wang
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Clinical Research
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Presence of innate lymphoid cells in allogeneic hematopoietic grafts correlates with reduced graft-versus-host disease
Anna Kroeze, Vera van Hoeven, Myrddin W. Verheij, Annelies W. Turksma, Naomi Weterings, Sofie van Gassen, Sacha S. Zeerleder, Bianca Blom, Carlijn Voermans, Mette D. Hazenberg
Open Access
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Response to extracorporeal photopheresis therapy of patients with steroid-refractory/-resistant GvHD is associated with up-regulation of Th22 cells and Tfh cells
Ming Ni, Lei Wang, Yuntian Ding, Wenjie Gong, Sanmei Wang, Brigitte Neuber, Maria-Luisa Schubert, Tim Sauer, Angela Hückelhoven-Krauss, Thomas Luft, Ute Hegenbart, Stefan Schönland, Volker Eckstein, Jishi Wang, William Krüger, Carsten Müller-Tidow, Peter Dreger, Michael Schmitt, Anita Schmitt
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Manufacturing
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Technical challenges for complete implementation of automated growth-based methods for microbiological examination of advanced therapy medicinal products. What's wrong with Candida albicans?
Antonio Rodríguez-Acosta, Jesús Chaparro-García, Inmaculada De-Toro, Rafael Maldonado-Sánchez, Raquel Muñoz-Fernández, Cristina Antúnez, Cecilia Frecha, Laura Leyva
Open Access
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Optimization of therapeutic T cell expansion in G-Rex device and applicability to large-scale production for clinical use
Elisa Gotti, Sarah Tettamanti, Silvia Zaninelli, Carolina Cuofano, Irene Cattaneo, Maria Caterina Rotiroti, Sabrina Cribioli, Rachele Alzani, Alessandro Rambaldi, Martino Introna, Josée Golay
Open Access
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Regulatory Practices
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An industry survey of implementation strategies for clinical supply chain management of cell and gene therapies
Lequina Myles, Terry David Church
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Validation plan of bone marrow collection, processing and distribution using the failure mode and effect analysis methodology: a technical report
Luciana Teofili, Maria Bianchi, Caterina Giovanna Valentini, Martina Bartolo, Nicoletta Orlando, Simona Sica
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