Abstract 24
Repetitive Intracranial Injection of NK Cells Engineered With a HER2-targeted CAR Alone and in Combination With Systemic Anti-PD-1 Checkpoint Inhibition in Recurrent Glioblastoma Patients

Elisabeth Ehrend, PhD
DRK Blutspendedienst Baden-Wurttemberg - Hessen
Germany

Abstract 1132
Mechanistic Insights into T Cell Recognition of a Novel Splicing-Derived Noncanonical Antigen

Conrad Russell Y. Cruz, MD, PhD
Children's National Research Institute
United States

Abstract 1272
Towards a Universal Lipid Nanoparticle (LNP) Platform for Multiplex Engineering of Next-Generation Ex Vivo Cell Therapies

Martin Rabel, Dr. rer. Nat.
Cytiva
Germany

Abstract 1
Jurisdictional Loopholes in Accelerated Regulatory Schemes Drive Unsafe Stem Cell Tourism Across the APAC Region

Hamid Bidkhori, MD, PhD
Hudson Institute of Medical Research
Australia

Abstract 21
Multimodal CAR-TA T Cell Therapy Combining B7H3 and PRAME Targeting With TNG–TGFBTII Armoring Elicits Enhanced Anti–tumor Potency in Solid Tumor Models

Kajal Chaudhry, PhD
Children's National Hospital
United States

Abstract 74
Immune-driven Activation of Hair Follicle Stem Cells as a Translational Model for Future Cell-based Therapy Development

Sabrina Mai-Yi Fan, PhD
National Taiwan University Hospital
Taiwan

Abstract 9
Mesenchymal Stromal Cells Influence the Epigenetic Landscape of Trained Macrophages in a Clinically Relevant Model of Allergic Asthma

Molly Dunlop, BSc
Maynooth University
Ireland

Abstract 64
Targeting Microglial P2X7R Using Non-viral siRNA Delivered via an Injectable Hydrogel as a Treatment for Drug-refractory Temporal Lobe Epilepsy

Anne Marie O'Callaghan, BSc
Royal College of Surgeons in Ireland
Ireland

Abstract 79
Natural Killer Cells Genetically Modified to Overexpress the Death Ligand Trail Can Partially Overcome the Immunosuppressive Effects of the Leukemic Bone Marrow Microenvironment

Leonie Durkan, MSc
University of Galway
Ireland

Abstract 83
Metabolic Reprogramming Enhances Stem-like and Functional Properties of Lung Cancer-derived TILs

Abhishek Tomar, MSc
The Lambe Institute for Translational Research, University of Galway
Ireland

Abstract 75
Clinical Translation of Colon Organoid Regenerative Medicine (ATORM-C): From Preclinical Optimization to First-in-Human Proof-of-Concept in Refractory Intestinal Ulcers

Kyung Jin Lee, PhD
ORGANOIDSCIENCES LTD.
Republic of Korea

Abstract 4
Data-driven Approach to Growing a Cell and Gene Therapy (CGT) Laboratory: Memorial Sloan Kettering Cancer Center (MSKCC) Cell Therapy Laboratory (CTL) Experience.

Elena Maryamchik, MD, MBA
Memorial Sloan Kettering Cancer Center
United States

Abstract 45
VivoCell: An Accessible Delivery System With Proven Efficacy for In Vivo Engineering of T Cells

Hailey Edelstein, PhD
Syenex
United States

Abstract 600
UMAP-guided Spatial MALDI Workflow for Rapid, Reproducible Metabolic Characterization of Neural Rosettes

Oluwatomisin Adebayo, BS
Georgia Institute of Technology
United States

Abstract 56
Adipose Tissue-derived Mesenchymal Stromal Cells and Their Extracellular Vesicles Are Functionally Deficient in Patients With Systemic Sclerosis

Dalia Ibarissen, MS
Institute for Regenerative Medicine and Biotherapy - INSERM U1183
France

Abstract 20
Depletion of Pathogenic B Cells and Autoantibodies in Systemic Lupus Erythematosus Using IGHV4-34 B Cell Receptor Targeted CAR T Cells

Audrey Bochi-Layec, BA
University of Pennsylvania
United States

Abstract 23
iPSC-derived Macrophages Engineered to Express IL-12 Modulate the Tumor Microenvironment and Support T Cell Lysis of Ovarian Cancer Models

Ian Hay, BS
Factor Bioscience Inc.
United States

Abstract 602
Bridging Scale-up to Transplantation: Pluripotent Stem Cell-derived Pancreatic Islet Encapsulation in Emulsion-generated High Concentration Alginate Beads

Arianna Castro Rojas, MEng
McGill University
Canada

Abstract 77
Developing Allogeneic Off-The-Shelf Retinal Pigmented Epithelium (RPE) Cell Therapy for Dry-age Related Macular Degeneration: Chemistry, Manufacturing, and Controls (CMC), Pre-clinical Studies, Safety and Efficacy Results From an Ongoing Ph 1/2a Clinical Trial

Rajarshi Pal, PhD
Eyestem Research
India

Abstract 19
Adoptive Cell Therapy With CD45RA-/CR45RO+ Memory T Lymphocytes to Treat Infectious Diseases in Immunocompromised Patients

Karima Al-Akioui-Sanz, MS
IdiPAZ-CNIO Pediatric Hemato-Oncology Clinical Trial Unit
Spain

Abstract 47
Therapeutic Rescue of Treg Dysfunction: Supraphysiological CTLA-4 Expression for Autoimmune Disease Treatment

Magdalena Piotrowska-Mieczkowska, PhD
PolTREG SA
Poland

Abstract 68
Gene Therapy for Recombinase Deficient-SCID

Frank Staal, PhD
Leids Universitair Medisch Centrum
Netherlands

Abstract 73
Antibody Based Purification Using CD99R Generates Pure and Highly Functional Stem Cell Derived Islets

Eda Erbil, MSc
Karolinska Institute
Sweden

Abstract 44
Generation of Transgenic T Cell Receptor T Cells (TGTCR T) Targeting Invasive Fungal Infections

Deekshitha Dhulipati, BMedSci (Honours)
The Westmead Institute for Medical Research/University of Sydney
Australia

Abstract 22
Bioenergetics and Cytotoxicity Reinforcement of Natural Killer Through Mitochondrial Transfer From Mesenchymal Stem Cells: A Novel Strategy for Cellular Immunotherapy

Pablo Castro-Córdova, PhD
Center IMPACT - Universidad de los Andes
Chile

Abstract 1531
Combining Genetic Engineering and Scalable Production of Stem Cell-derived Pancreatic Islets to Enable Allogeneic Cell Replacement Therapy in Insulin-dependent Diabetes

Natasha Hui Jin Ng, PhD
BetaLife Pte Ltd
Singapore

Abstract 32
ICAM-1 Knock Out Hypoimmune Pluripotent Stem Cell Therapies for Cardiovascular Disease and Type 1 Diabetes

Matthew E. Brown, PhD
University of Wisconsin-Madison
United States

Abstract 66
AI-driven Optimization of Hyperbranched Poly(Amino Ester)s for CFTR Gene Delivery in a Cystic Fibrosis Mouse Model

Xianqing Wang, PhD
University College Dublin
Ireland